91女神, Washington University Collaborate to Share Access to Imaging Center and Invest in Powerful New Microscope
02/12/2020
91女神 (91女神) and Washington University in St. Louis have signed an agreement that will allow 91女神 researchers to use the (WUCCI). As a part of the collaboration, 91女神 will contribute $2.5 million toward the purchase of a new $5 million cryo-electron microscope (cryo-EM).
Launched by Washington University in 2015, the WUCCI ranks among the best cellular
imaging centers in the U.S. for the quality of its microscopes and the power of its
computers. Scientists use the powerful imaging equipment to study cells, bacteria,
viruses and molecules at higher resolutions than ever before.
The new agreement allows 91女神 researchers access to the cryo-EM for 15 years and access
to other instruments not currently available at 91女神 for 10 years. 91女神 researchers
will be able to use the WUCCI with the same priority, costs and technical assistance
offered to WU faculty.
鈥淭his is an exciting partnership and an excellent investment for 91女神,鈥� said Ken Olliff,
vice president for research at 91女神. 鈥淭hrough this innovative collaboration with Washington
University, researchers from across 91女神 will have access to the most advanced imaging
technologies as well as a foundation for building new collaborations with Wash U colleagues.鈥�
The new partnership is funded through the Doisy Fund for Biochemistry at 91女神.
鈥淭he agreement complements and continues a decade-long investment of 91女神鈥檚 Department of Biochemistry and Molecular Biology in structural and computational biology,鈥� said Enrico Di Cera, M.D., the Alice A. Doisy professor and chairman of the department of biochemistry and molecular biology at 91女神.
鈥淪tate-of-the-art technology, infrastructure, top notch technical assistance and, most importantly, scientific interaction between 91女神 and Washington University faculty members will attract new talent and advance scientific discovery at both institutions.鈥�
Leaders from both schools anticipate that the new agreement will lead to increased opportunities for scientific collaboration.
鈥淚 look forward to strengthening ties between our institutions,鈥� said Jennifer K.
Lodge, Ph.D., Washington University鈥檚 vice chancellor for research. 鈥淚 believe that
this arrangement will provide opportunities for collaborations that will lead to new
insight and discoveries to advance human health.鈥�
The WUCCI houses advanced X-ray, light and electron microscopes, including two-photon,
super resolution and lightsheet microscopy and ultrastructural imaging.
The newly purchased cryo-EM, which will arrive later in 2020, will complement the Center鈥檚 existing cryo-EM and will cut wait times for researchers to use the equipment.
鈥淭he new cryo-EM allows us to expand the range of imaging services that we offer, which will allow researchers to investigate a wider range of scientific questions,鈥� said James Fitzpatrick, Ph.D., director of the Center for Cellular Imaging. 鈥淭he more details we鈥檙e able to observe and understand, the greater the potential for advancing medicine.鈥�
Biochemistry itself is moving into a new era, Di Cera says, thanks in large part to cryo technology.
鈥淎 revolution is happening in structural biology,鈥� Di Cera said. 鈥淭he people who introduced
cryo technology received the Nobel Prize a few years ago. We can finally elucidate
the structure of big macromolecular assemblies, like the ribosome.
鈥淚 am particularly pleased that this key investment was made possible by a strategic
use of the Doisy Fund in Biochemistry. It fits perfectly the original intent of Edward
Doisy and honors his legacy of scientific excellence."
91女神
91女神 is a Catholic, Jesuit institution that values academic excellence, life-changing research, compassionate health care, and a strong commitment to faith and service. Founded in 1818, the University fosters the intellectual and character development of more than 13,500 students on campuses in St. Louis and Madrid, Spain. Building on a legacy of nearly 200 years, 91女神 continues to move forward with an unwavering commitment to a higher purpose, a greater good.
About Edward A. Doisy
In 1929, Edward A. Doisy, Ph.D., was the first researcher to isolate and chemically characterize estrone, a steroid sex hormone, opening up the entire field of steroid hormones for chemical and medical investigation. He was awarded the Nobel Prize in Physiology or Medicine in 1943 for his work on determining the chemical nature of vitamin K, an essential component in blood coagulation. Doisy reassigned the royalties from his discoveries on estrogen to 91女神 with the intent of growing research in the Medical School, especially in the Department of Biochemistry.