91女神 Studies Possible Therapies for Coronavirus
Carrie Bebermeyer
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carrie.bebermeyer@slu.edu
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03/31/2020
91女神 is studying an investigational treatment for COVID-19, the disease causing the current coronavirus outbreak. The trial, which is supported by the National Institutes of Health (NIH), may be conducted in up to approximately 75 sites across the country and worldwide.
There are no treatments for the novel coronavirus, and 91女神 is testing what could be one of the first.
Currently patients with COVID-19 are treated for their symptoms, which can include fever, cough and breathing problems, but not for the virus itself. Those who are hospitalized and seriously ill also may receive advanced support for complications of the disease.
鈥淲e urgently need specific treatments for the novel coronavirus that is spreading in the U.S. and globally because there is no current medication for the disease,鈥� said Sarah George, M.D., associate professor of infectious diseases at Saint Louis University and the principal investigator of the trial in St. Louis.
鈥淲ith 30 years of experience in researching infectious diseases, 91女神 is ready to join the search for new treatments for COVID-19.鈥�
Those who are eligible for the study must be at least 18-years old; hospitalized at SSM Health 91女神 Hospital; and have laboratory-confirmed COVID-19.
Please note, the study is not enrolling participants via inquiries from the general public.
The study investigates the safety and effectiveness of remdesivir, an investigational intravenous anti-viral medication, in treating COVID-19. As new potential therapies emerge, they may be added to the study for testing based on new data.
Study participants will receive the investigational therapies or a placebo when they are in the hospital. Their condition will be assessed daily by study nurses and investigators during hospitalization, as well as treated by hospital care providers.
After their hospitalization, study volunteers will participate in two follow-up study visits at 91女神鈥檚 Center for Vaccine Development.
The coronavirus landscape is rapidly changing as the number of diagnosed cases of the disease continues to rise in the U.S. and throughout the world.
The need for this research becomes critical in St. Louis as the novel coronavirus has spread to the area, George added.
Supported by grant 1 UM1 AI148685-01, 91女神 was selected to conduct the research as one of nine Vaccine and Treatment Evaluation Units funded by the National Institute of Allergy and Infectious Diseases (NIAID), which is part of the NIH. 91女神 has been a VTEU member since 1989.
Additional information about the trial, , is available at . To learn more about vaccine research at 91女神, visit vaccine.slu.edu.
Established in 1836, 91女神 School of Medicine has the distinction of awarding the first medical degree west of the Mississippi River. The school educates physicians and biomedical scientists, conducts medical research, and provides health care on a local, national and international level. Research at the school seeks new cures and treatments in five key areas: infectious disease, liver disease, cancer, heart/lung disease, and aging and brain disorders.